Tru Niagen Review


We all wish the time to slow down, yet aging is an inevitable series of natural processes that we all will face sooner or later. As we are getting old, the body experiences some changes, good and bad. When the first signs and symptoms of aging such as wrinkles and weakness occur, many people start searching for ways to postpone the aging processes. 

The anti-aging market, in turn, offers a great number of procedures and products, including hormone replacement therapies, surgical procedures, and supplements. 

The product that has taken my attention is Tru Niagen. I have heard a lot about the benefits of NAD+ from Chris Masterjohn and Dr. Rhonda Patrick and have been keen to try this for a while, this is why I have been experimenting with Tru Niagen for the last couple of months. I expect to see more results the longer I take this, and this is my own personal experiment and just one of a number of things that I do to optimize my health.

This supplement doesn’t promise you eternal youth or longer life. The aim of Tru Niagen is not to simply help you extend your life but to help you age better. Check out my Tru Niagen review to find out how Tru Niagen works, its pros and cons, and whether this dietary supplement is right for you.

What Is Tru Niagen?

Tru Niagen is a supplement designed to boost nicotinamide adenine dinucleotide (NAD) levels. Its main active ingredient is nicotinamide riboside (NR), which our body converts to NAD.

Who Needs Tru Niagen?

If you're a young person full of energy, you  don’t really need this kind of supplement. However, you might like to try Tru Niagen as a preventive strategy. I this case, it’s better to consult your physician first.  

Tru Niagen is more suitable for people in the 40s and above when NAD levels naturally start to drop. So, if you want to age better, stay active and productive as you age, Tru Niagen might help you and boost your energy levels. 

If to combine exercising, a healthy diet, and supplementation with a NAD-booster like Tru Niagen, you can significantly extend your active years.

How To Use Tru Niagen? 


TRU Niagen is available in capsules and portable stick packs. 

The recommended dose is 2 of the 150 mg capsules a day. You can take it with or without food, in the morning or at night. 

The company recommends customers take 2 of the 150 mg capsules a day with or without food. Capsules can be taken either in the morning or at night and either with or without food.

As for the portable stick packs, each pack contains a daily dose of NR combined with fiber. Just combine one pack with 16 ounces of a cold beverage and drink it.

How Does Tru Niagen Work? 

Tru Niagen is not a stimulant, yet it helps regulate energy production at the cellular levels. You may experience improved energy levels already in a couple of weeks of supplementation. 

In one month, by increasing your NAD levels, you’ll enhance cell repair and make your cells more resilient. 

If you make the intake of Tru Niagen your daily routine, you’re likely to improve your quality of life, reduce fatigue and sustain energy throughout each day.

The Science Behind NAD Anti-Aging Effects

What is the Importance of NAD?

Your overall health depends on your cellular health a lot. NAD is a critical coenzyme that helps create cellular energy, support cellular repair throughout your body, and fortify cellular antioxidant defense system. 

It also plays a vital role in many fundamental physiological processes:

  • The clinical studies show that it helps support a healthy mitochondrial function, metabolism and processes such as oxidative phosphorylation, which is converting the food we eat into energy that our cells can use.
  • It may improve your sleep by helping you reset your internal clock, regulate your circadian rhythms and sleep-wake cycles.

As we age, the NAD levels decline, which increases the risk of heart disease, elevated blood pressure, diabetes, and degenerative diseases such as Alzheimer’s disease. 

Therapeutic Potential of Boosting NAD


By increasing NAD levels, you may offset many of the effects of aging and age gracefully. These are potential health benefits of NAD-boosters:

  • It boosts immune system and regulates inflammation
  • It helps support brain function, slow down sensory impairment and cognitive decline
  • It promotes gluconeogenesis in the liver and lipogenesis in adipose tissue
  •  It helps improve insulin sensitivity
  • It reduce the chance of cardiovascular and cerebrovascular diseases
  • It has protective effects against acute kidney injury

Tru Niagen Pros and Cons



  • Boosts NAD+ levels, showing the first positive results already in a couple of weeks. Many human trials using Niagen have been conducted.
  • Tru Niagen may help you improve metabolism, feel more energetic and productive, and maintain good sleep patterns. 
  • Unlike Niacinamide, TRU Niagen does not cause skin flushing and does not suppress sirtuin activity.
  • It doesn’t contain caffeine, nuts, gluten, animal byproducts, artificial colors, or flavors.
  • Tru Niagen has been successfully reviewed under the FDA's new dietary ingredient (NDI) notification program. It has also been generally recognized as safe (GRAS).
  • True Niagen bears the NSF Certified for Sport® seal, which ensures that the supplement doesn’t contain any harmful ingredients.
  • This supplement has obtained regulatory acceptance in  Canada, the European Union, and Australia.


  • It may take several weeks or months to increase NAD levels and notice health improvements.
  • It should not be used for treatment or taken as preventive measures of the disease.
  • You can keep optimal NAD levels only by consistent supplementation.
  • The chance of experiencing side effects is low. However, taking high doses may cause nausea, indigestion, headache, diarrhea.
  • You should be careful with Tru Niagen while taking other medications. For instance,  Tru Niagen may lower blood pressure, therefore, you should be careful with taking blood pressure medication.
  • There is no money-back guarantee. If you’re not satisfied with the supplement, unfortunately, there’s no return for the product which is not in original factory-sealed condition.

Tru Niagen vs Basis 

Tru Niagen by ChromaDex is not the only supplement that contains Nicotinamide Riboside. Its main competitor in the anti-aging market is Elysium's Basis

So, you’re probably wondering which of the two available types is better for you. 

Here is a simple comparison chart with the key differences between Tru Niagen and Basis.

Are NR Supplements Safe?

The clinical trials on Tru Niagen funded by ChromaDex show that NR supplements are safe and may boost NAD levels in about 6-8 weeks helping the person cope with the aging process better.

However, more research is needed to find more evidence that nicotinamide riboside chloride has positive effects on your health levels, helps slow the aging process, and protect against age-related diseases.
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